Frontiers in Neurosurgery

Frontiers in Neurosurgery

Volume: 4

Craniopharyngiomas - Classification and Surgical Treatment

Indexed in: Scopus, EBSCO.

Craniopharyngiomas are a type of brain tumour in the suprasellar region with benign histological and cellular features. Clinical manifestations of craniopharyngiomas include decreased vision, ...
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Intraventricular Craniopharyngioma?

Pp. 254-282 (29)

Jun Pan and Yuntao Lu


As we known, adamantinomatous craniopharyngioma (ACP) is thought to originate from residual Rathke’s pouch cells along the long axis from nasopharynx to infundibulum [1, 2]. However, the squamous papillary subtype of CP (SPCP) is believed to occur throught squamous metaplasia in the pars tuberalis [2, 3]. In consideration of these inferences, the neural parenchymal layer of third ventricular floor (3rd VF) should locate above the CP, separate both the tumor and third ventricular chamber. However, the first study conducted by Dubos et al. in 1953 extensively reported the tumors completely located inside the third ventricle cavity by autopsy or intraoperative finding [4-13]. Because of this topographical location, the theory of CP origin has been challenged and much more neurosurgeons are interested in pursuing the true morphological characteristics and diagnostic criteria of these tumors [9, 14]. In this chapter, we firstly reviewed the definition of the intraventricular CP in several publications. Then based on our histological and clinical study, the true morphology of intraventricular CP was proposed. The related approach selection and surgical skills was also depicted.


Craniopharyngioma, Intraventricular, Third ventricular floor.


Department of Neurosurgery, Nanfang Neurosurgery Research Institution, Nanfang Hospital, Southern Medical University, 1838 North Guangzhou Avenue, Guangzhou, China.