Natural Bioactive New Withanolides

Author(s): Qian-Qian Xu, Kui-Wu Wang*

Journal Name: Mini-Reviews in Medicinal Chemistry

Volume 20 , Issue 12 , 2020

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Graphical Abstract:


Withanolides are a group of highly oxygenated steroids derived from a C28 ergostane skeleton, and have attracted significant scientific interest due to their complex structural features and multiple bioactivities. More than 170 new natural withanolides were isolated and identified in the last 5 years. This review provides a comprehensive summary of the structural, biological and pharmacological activities of these new compounds.

Keywords: Withanolide, structure, biological activities, anti-inflammatory, oxygenated steroids, antistress.

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Article Details

Year: 2020
Page: [1101 - 1117]
Pages: 17
DOI: 10.2174/1389557518666171129164056
Price: $65

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