One-pot Synthesis of Aurones through Oxidation-cyclization Tandem Reaction Catalyzed by Copper Nanoparticles Catalyst

Title:One-pot Synthesis of Aurones through Oxidation-cyclization Tandem Reaction Catalyzed by Copper Nanoparticles Catalyst

Volume: 15 Issue: 1

Author(s): Min Yu, Guangxiang Liu , Chengyan Han, Li Zhu and Xiaoquan Yao*

Affiliation:

• College of Material Science and Technology, Nanjing University of Aeronautics and Astronautics, Nanjing 210016,China

Keywords: Aurones, bipyridine, oxidation-cyclization, tandem reaction, copper nanoparticles, oxygen oxidation.

Abstract: Aurones were synthesized through an oxidation-cyclization tandem reaction of 2-(1- hydroxyprop-2-ynyl)phenols catalyzed by copper nanoparticles (Cu NPs) with bipyridine as the ligand. In the reaction, oxygen worked as a green and mild oxidant to give the best results. Cu NPs were dually activated by bipyridine ligand and water, and showed highly efficient catalytic activities to the oxygen oxidation and the cylization to give aurones and flavonoids.

Cite this article as:

Yu Min , Liu Guangxiang , Han Chengyan , Zhu Li and Yao Xiaoquan *, One-pot Synthesis of Aurones through Oxidation-cyclization Tandem Reaction Catalyzed by Copper Nanoparticles Catalyst, Letters in Organic Chemistry 2018; 15 (1) . https://dx.doi.org/10.2174/1570178614666171110150853