A Review of the Current Role of Blood Clotting Analyzers in Clinical Practice

Author(s): Karan Sarode*, Saad S. Hussain, Alan Tyroch, Debabrata Mukherjee

Journal Name: Cardiovascular & Hematological Disorders-Drug Targets
Formerly Current Drug Targets - Cardiovascular & Hematological Disorders

Volume 17 , Issue 3 , 2017


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Abstract:

Background: Viscoelastic tests (VETs) such as thromboelastography, rotational thromboelastography, and the Sonoclot Analyzer assess the entire process of clot formation through dissolution in real-time, and may provide additional therapeutic value to conventional laboratory coagulation tests. With the ability to obtain rapid results and identify specific coagulopathies, VETs has been examined in a variety of clinical scenarios, including cardiac surgery, trauma, obstetric emergencies, and liver transplant.

Conclusion: This review provides a summary of clinical trials utilizing VETs in the aforementioned clinical scenarios, and suggests that VETs have demonstrated a capability to identify coagulopathies, utility in guiding algorithms to reduce the amount of transfusions, and a limited ability to predict bleeding events or mortality.

Keywords: Viscoelastic tests, clot analyzer, coagulopathy, trauma, surgery, coagulation tests.

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Article Details

VOLUME: 17
ISSUE: 3
Year: 2017
Page: [167 - 179]
Pages: 13
DOI: 10.2174/1871529X17666171030120851
Price: $65

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