Abstract
Background: Viscoelastic tests (VETs) such as thromboelastography, rotational thromboelastography, and the Sonoclot Analyzer assess the entire process of clot formation through dissolution in real-time, and may provide additional therapeutic value to conventional laboratory coagulation tests. With the ability to obtain rapid results and identify specific coagulopathies, VETs has been examined in a variety of clinical scenarios, including cardiac surgery, trauma, obstetric emergencies, and liver transplant.
Conclusion: This review provides a summary of clinical trials utilizing VETs in the aforementioned clinical scenarios, and suggests that VETs have demonstrated a capability to identify coagulopathies, utility in guiding algorithms to reduce the amount of transfusions, and a limited ability to predict bleeding events or mortality.
Keywords: Viscoelastic tests, clot analyzer, coagulopathy, trauma, surgery, coagulation tests.
Cardiovascular & Hematological Disorders-Drug Targets
Title:A Review of the Current Role of Blood Clotting Analyzers in Clinical Practice
Volume: 17 Issue: 3
Author(s): Karan Sarode*, Saad S. Hussain, Alan Tyroch and Debabrata Mukherjee
Affiliation:
- Paul L. Foster School of Medicine, El Paso, Texas, TX,United States
Keywords: Viscoelastic tests, clot analyzer, coagulopathy, trauma, surgery, coagulation tests.
Abstract: Background: Viscoelastic tests (VETs) such as thromboelastography, rotational thromboelastography, and the Sonoclot Analyzer assess the entire process of clot formation through dissolution in real-time, and may provide additional therapeutic value to conventional laboratory coagulation tests. With the ability to obtain rapid results and identify specific coagulopathies, VETs has been examined in a variety of clinical scenarios, including cardiac surgery, trauma, obstetric emergencies, and liver transplant.
Conclusion: This review provides a summary of clinical trials utilizing VETs in the aforementioned clinical scenarios, and suggests that VETs have demonstrated a capability to identify coagulopathies, utility in guiding algorithms to reduce the amount of transfusions, and a limited ability to predict bleeding events or mortality.
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Cite this article as:
Sarode Karan *, Hussain S. Saad , Tyroch Alan and Mukherjee Debabrata , A Review of the Current Role of Blood Clotting Analyzers in Clinical Practice, Cardiovascular & Hematological Disorders-Drug Targets 2017; 17 (3) . https://dx.doi.org/10.2174/1871529X17666171030120851
DOI https://dx.doi.org/10.2174/1871529X17666171030120851 |
Print ISSN 1871-529X |
Publisher Name Bentham Science Publisher |
Online ISSN 2212-4063 |
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