Abstract
Background: although neonatal pain management has seen huge improvements in the past years, many gaps between knowledge and practice still exist.
Objective: to give the reader the state of the art of actual pain management and treatment. Methods: a literature review was done on the physiopathology of pain, sex differences in the perception of pain, epidemiology, non-pharmacological treatment and developmental care approach, pharmacological treatment with pharmacokinetics and pharmacodynamics approaches. Conclusion: despite an increasing knowledge in the field of neonatal pain, many gaps and questions remain, especially relative to the lack of assessment, prevention and treatment of painful procedures, appropriate drugs and dosing to support the well-being and the brain development of this highly vulnerable population.Keywords: Pain, neonate, physiopathology, sex-differences, epidemiology, analgesic treatments, developmental care.
Current Pharmaceutical Design
Title:Neonatal Pain, Still Searching for the Optimal Approach
Volume: 23 Issue: 38
Author(s): Elizabeth Walter-Nicolet*, Laurent Calvel*, Geraldine Gazzo, Pierrick Poisbeau and Pierre Kuhn
Affiliation:
- Medicine and Neonatal Intensive Care Unit. Groupe hospitalier Paris Saint Joseph. Paris,France
- Centre National de la Recherche Scientifique and University of Strasbourg, Institute for Cellular and Integrative Neuroscience (INCI), Strasbourg,France
Keywords: Pain, neonate, physiopathology, sex-differences, epidemiology, analgesic treatments, developmental care.
Abstract: Background: although neonatal pain management has seen huge improvements in the past years, many gaps between knowledge and practice still exist.
Objective: to give the reader the state of the art of actual pain management and treatment. Methods: a literature review was done on the physiopathology of pain, sex differences in the perception of pain, epidemiology, non-pharmacological treatment and developmental care approach, pharmacological treatment with pharmacokinetics and pharmacodynamics approaches. Conclusion: despite an increasing knowledge in the field of neonatal pain, many gaps and questions remain, especially relative to the lack of assessment, prevention and treatment of painful procedures, appropriate drugs and dosing to support the well-being and the brain development of this highly vulnerable population.Export Options
About this article
Cite this article as:
Walter-Nicolet Elizabeth*, Calvel Laurent*, Gazzo Geraldine, Poisbeau Pierrick and Kuhn Pierre, Neonatal Pain, Still Searching for the Optimal Approach, Current Pharmaceutical Design 2017; 23 (38) . https://dx.doi.org/10.2174/1381612823666171017164957
DOI https://dx.doi.org/10.2174/1381612823666171017164957 |
Print ISSN 1381-6128 |
Publisher Name Bentham Science Publisher |
Online ISSN 1873-4286 |
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