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Current Pharmaceutical Design

Editor-in-Chief

ISSN (Print): 1381-6128
ISSN (Online): 1873-4286

Review Article

Neonatal Pain, Still Searching for the Optimal Approach

Author(s): Elizabeth Walter-Nicolet*, Laurent Calvel*, Geraldine Gazzo, Pierrick Poisbeau and Pierre Kuhn

Volume 23, Issue 38, 2017

Page: [5861 - 5878] Pages: 18

DOI: 10.2174/1381612823666171017164957

Price: $65

Abstract

Background: although neonatal pain management has seen huge improvements in the past years, many gaps between knowledge and practice still exist.

Objective: to give the reader the state of the art of actual pain management and treatment.

Methods: a literature review was done on the physiopathology of pain, sex differences in the perception of pain, epidemiology, non-pharmacological treatment and developmental care approach, pharmacological treatment with pharmacokinetics and pharmacodynamics approaches.

Conclusion: despite an increasing knowledge in the field of neonatal pain, many gaps and questions remain, especially relative to the lack of assessment, prevention and treatment of painful procedures, appropriate drugs and dosing to support the well-being and the brain development of this highly vulnerable population.

Keywords: Pain, neonate, physiopathology, sex-differences, epidemiology, analgesic treatments, developmental care.


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