Background: Quinoxaline is an important nucleus used in the development of novel potentially
bioactive structures. Hence, the development of new methodologies that provide access to this
scaffold in shorter times and increased yields is of interest. In this work, we review many interesting
microwave-assisted methodologies for the synthesis of quinoxalines reported from 2007 to 2015.
Methods: The most prominent methods for the synthesis of quinoxalines under microwave irradiation
published in articles from 2007-2015 are reviewed.
Conclusion: Microwave irradiation proved to be a useful tool, providing many advantages on the synthesis
of this class, such as shorter reaction times, higher yields and better selectivity, when compared
to classical procedures.