Abstract
Background: Silver nanoparticle (Ag NP)-containing biolpolymer nanocomposites possess antibacterial activity, which is largely associated with the NP size, shape, surface area and medium.
Methods: These biomaterials have been investigated as dressing for wounds and burns, treatment for infected areas, coatings for orthopaedic and dental implants and for water disinfection.
Results: This broad-acting and potent antibacterial activity is likely due to a multifaceted mechanism of action that is not completely understood. Although the Ag NPs are useful against antibiotic resistant bacteria, their level of toxicity is not well established and requires further investigation.
Conclusion: This review details the brief perspective, critical analysis of the currently available articles and discusses the future applications of these potentially life-saving nanocomposites.
Keywords: Antibacterial, infectious diseases, nanoparticles, silver, biopolymers, chitosan, polycaprolactone, polyurethane, bone, dental, orthopedic, water disinfection.
Current Analytical Chemistry
Title:Recent Advances in Silver Nanoparticle Containing Biopolymer Nanocomposites for Infectious Disease Control – A Mini Review
Volume: 14 Issue: 3
Author(s): Md. A. Wahab*, Nazrul Islam, M. Enamul Hoque and David James Young
Affiliation:
- Faculty of Science, Health, Education and Engineering, University of Sunshine Coast, Maroochydore DC, Queensland 4558,Australia
Keywords: Antibacterial, infectious diseases, nanoparticles, silver, biopolymers, chitosan, polycaprolactone, polyurethane, bone, dental, orthopedic, water disinfection.
Abstract: Background: Silver nanoparticle (Ag NP)-containing biolpolymer nanocomposites possess antibacterial activity, which is largely associated with the NP size, shape, surface area and medium.
Methods: These biomaterials have been investigated as dressing for wounds and burns, treatment for infected areas, coatings for orthopaedic and dental implants and for water disinfection.
Results: This broad-acting and potent antibacterial activity is likely due to a multifaceted mechanism of action that is not completely understood. Although the Ag NPs are useful against antibiotic resistant bacteria, their level of toxicity is not well established and requires further investigation.
Conclusion: This review details the brief perspective, critical analysis of the currently available articles and discusses the future applications of these potentially life-saving nanocomposites.
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Cite this article as:
Wahab A. Md. *, Islam Nazrul , Hoque Enamul M. and Young James David , Recent Advances in Silver Nanoparticle Containing Biopolymer Nanocomposites for Infectious Disease Control – A Mini Review, Current Analytical Chemistry 2018; 14 (3) . https://dx.doi.org/10.2174/1573411013666171009163829
DOI https://dx.doi.org/10.2174/1573411013666171009163829 |
Print ISSN 1573-4110 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6727 |
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