Recent Progress of Novel Steroid Derivatives and Their Potential Biological Properties

Author(s): Shaoyong Ke*

Journal Name: Mini-Reviews in Medicinal Chemistry

Volume 18 , Issue 9 , 2018

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Graphical Abstract:


Steroid and its derivatives have been proved to have important and diverse biological functions, which present the wide spectrum of biological activities such as antitumor, antiviral, antibacterial, antimicrobial, antifungal, antioxidant, insecticidal, aromatase inhibitors, 5α-reductase inhibitors and neuromuscular blocking agents etc. Versatile features of steroid-derived compounds have emerged, so the aim of the present paper is to review the recent advances of steroid-based derivatives mainly focused on their structures and biological applications, which can be employed for further development to discover potential drug candidates.

Keywords: Biological properties, derivatives, diversity, recent progress, steroid, structure.

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Article Details

Year: 2018
Page: [745 - 775]
Pages: 31
DOI: 10.2174/1389557517666171003103245
Price: $65

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PDF: 36
PRC: 1