Recent Advances in the Application of the Heck Reaction in the Synthesis of Heterocyclic Compounds: An Update

Author(s): Majid M. Heravi*, Razieh Moradi*, Masoumeh Malmir

Journal Name: Current Organic Chemistry

Volume 22 , Issue 2 , 2018

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Graphical Abstract:


Background: The reaction of aryl halides or vinyl halides with activated alkenes in the presence of Palladium-catalyst along with a base for the formation of the C-C bond is called the Heck reaction. This reaction has been employed extensively in the synthesis of heterocyclic compounds.

Methodology: We have highlighted these applications in 2010.

Conclusion: This review aims to cover the recent application of the Heck reaction in the synthesis of heterocyclic compounds during a period from 2010 to 2017.

Keywords: Heck reaction, heterocyclic compounds, Pd, palladium, carbon-carbon bond formation, catalysis.

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Article Details

Year: 2018
Page: [165 - 198]
Pages: 34
DOI: 10.2174/1385272821666171002121126
Price: $58

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PDF: 35