Hypertension can be referred to as modern scourge in 2017 and although, it seems that an improvement
has been done during the passage of time, the full treatment still remains an unmet achievement for clinicians.
Hypertension incidence in Mediterranean countries, especially Greece and Turkey, seems to be increasing irrespective
of the expected protective effect of Mediterranean diet. The changed lifestyle and dietary habits of both
populations led to advanced cardiovascular events and arteriosclerosis both of which are linked with high blood
pressure. From statistic aspect, as in this work reviewed, it has been found out that gender, age, sociodemographic
characteristics and geographical location could promote the hypertension prevalence. Given the
above, as well as the fact that the current pharmaceutical formulations do not present the optimal results on hypertension
management, summing up the ongoing research on hypertension field is in high demand. Consequently,
the development of novel solutions for high blood pressure management either with new synthesized drugs or
fascinated drug delivery systems is required. Moreover, adopting healthy lifestyle and diet also plays a crucial
role against hypertension. This review is aimed at assisting researchers working on hypertension management by
summarizing update guidelines, various case reports describing hypertension related with other diseases, current
medications and newly synthesized drug delivery systems recently found in literature.