MIPs as a Versatile Tool for Micro-Solid-Phase Extraction and Probe Sensing

Author(s): Antonio Moreda-Pineiro, Juan Sanchez-Gonzalez, Maria Pilar Chantada-Vazquez, Ana Maria Bermejo, Pilar Bermejo-Barrera*

Journal Name: Current Chemical Biology

Volume 12 , Issue 2 , 2018

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Graphical Abstract:


Background: This review describes the use of molecularly imprinted polymers (MIPs) as tailor-made adsorbents for developing micro-solid phase extraction (µ-SPE) procedures when isolating/ assessing organic pollutants, drugs, and bioactive compounds from environmental, food, and clinical/ forensic samples.

Objective: Developments in MIP-µ-SPE are focused on synthesizing selective MIPs before preparing micro devices, and also when synthesizing MIPs onto nanoparticles such as magnetite (magnetic MIPs).

Conclusion: The current paper also reviews advances in MIPs synthesis onto quantum dots (MIP-QDs) for fluorescenssce sensing of organic compounds, advantages and drawbacks of each methodology, and future expected trends.

Keywords: Molecularly imprinted polymers (MIPs), micro-solid-phase, extraction, probe sensing, micro devices, quantum dots (MIP-QDs).

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Article Details

Year: 2018
Published on: 07 August, 2018
Page: [114 - 134]
Pages: 21
DOI: 10.2174/2212796811666170907151334
Price: $25

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PDF: 33