Recent Advances in Unique Sample Preparation Techniques for Biological and Environmental Analysis
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Akira Namera and Takeshi Saito
Remarkable techniques for the separation and detection of small quantities
of analytes have been developed in recent years. However, it is still difficult to directly
analyze species of interest in complex matrices. Although some methods have been
reported for direct injection into an analytical instrument, removal of interfering
substances during sample preparation is an important step in the analytical process.
This procedure is usually tedious and time consuming. To reduce the tedium of this
task and the time required for sample preparation, many unique extraction techniques
have been introduced and applied to the analysis of substances in environmental, food,
and biological samples. This chapter describes useful sample preparation techniques,
including conventional and newly developed ones, for determining analytes of interest
in biological, environmental, and food sources.
Headspace extraction, Liquid-liquid extraction, Microextraction,
Protein precipitation, Sample preparation, Solid-phase extraction.
Deaprtment of Forensic Medicine, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan.