Background: Recent studies have identified the correlation between dementia and certain
vocal features, such as voice and speech changes. Vocal features may act as early markers of Alzheimer's
disease (AD). Despite being present in non-pathological senescence and Mild Cognitive Impairment,
especially in its amnesic subtype (aMCI), these voice- and speech-related symptoms are the
first signs of AD. The purpose of this study is to verify whether these signs are related to deficits in lexical
access, which appear early in AD.
Method: Anomic deficits in persons with MCI and AD are assessed through tests on verbal memory,
denomination by confrontation, and verbal fluency. In addition, an acoustic analysis of speech is conducted
in a reading task to identify the acoustic parameters associated with the groups analyzed, and
their relation to the degree of anomic impairment observed in each one of them.
Results and Conclusions: The results show a direct relationship between the different acoustic parameters
present in AD and the verbal fluency tests results.