Title:Microwave Assisted Synthesis of Spiro Heterocyclic Systems: A Review
VOLUME: 22 ISSUE: 1
Author(s):Pankaj Khanna, Leena Khanna, Sean J. Thomas, Abdullah M. Asiri and Siva S. Panda*
Affiliation:Acharya Narendra Dev College, University of Delhi, Govindpuri, Kalkaji, New Delhi-110019, Guru Gobind Singh Indraprastha University, Sector-16 C, Dwarka, New Delhi-110078, Department of Chemistry & Physics, Augusta University, Augusta, Georgia 30912, Chemistry Department, Faculty of Science, King Abdulaziz University, Jeddah, 21589, Department of Chemistry & Physics, Augusta University, Augusta, Georgia 30912
Keywords:Spiro compounds, heterocycles, microwave, green synthesis.
Abstract:Background: Microwave irradiation has emerged as a useful synthetic strategy
for chemists and drug developers due to enhanced yields, regioselectivity, and faster reaction
times. One area of importance in its practice has been the design of spiro compounds,
which possess great interest on account of their natural occurrence and medicinal capabilities.
The increasingly large number of these scaffolds and unlimited amount of methodologies
utilized in their preparation have made them good candidates for the microwave
assisted approach.
Conclusion: Therefore, this review emphasizes the use of microwave irradiation in the
synthesis of spiro heterocyclic compounds.
