Ciliary Trafficking in Vertebrate Photoreceptors
Pp. 1-15 (15)
Cilia are microtubule-based extensions of the plasma membrane of cells.
These extensions detect extrinsic cues that are crucial for carrying out a myriad of
developmental and homeostatic signaling cascades. Cilia have evolved diverse means
to mediate signaling cascades in a cell-type specific manner. In this article, I have
summarized the conserved mechanisms of formation of cilia and their structural and
functional specialization for light detection.
Basal body, Cilia, Photoreceptor, Retina.
Department of Ophthalmology, UMASS Medical School, Worcester, MA, USA