Abstract
Background: Polysaccharides are widely found in animals, plants and micro- organisms, and are closely related to various physiological functions. It is one of the four basic substances that constitute life activities. Polysaccharide has antitumor, antivirus, antioxidant, immune regulation and other biological activities.
Objective: Because the polysaccharide has significant antitumor effect and small side-effects, it has become the focus of the current antitumor drug research.
Results: Herein, the polysaccharide species with antitumor effect were summarized in recent years, and the antitumor activity mechanisms of polysaccharides were analyzed and discussed.
Conclusion: Many polysaccharides have good antitumor activity, and they have broad application prospects.
Keywords: Polysaccharides, antitumor, biological activities, mechanisms, discuss, summarize.
Current Drug Targets
Title:Antitumor Activity of Polysaccharides: An Overview
Volume: 19 Issue: 1
Author(s): Ling Chen and Gangliang Huang*
Affiliation:
- Active Carbohydrate Research Center, College of Chemistry, Chongqing Normal University, Chongqing, 401331,China
Keywords: Polysaccharides, antitumor, biological activities, mechanisms, discuss, summarize.
Abstract: Background: Polysaccharides are widely found in animals, plants and micro- organisms, and are closely related to various physiological functions. It is one of the four basic substances that constitute life activities. Polysaccharide has antitumor, antivirus, antioxidant, immune regulation and other biological activities.
Objective: Because the polysaccharide has significant antitumor effect and small side-effects, it has become the focus of the current antitumor drug research.
Results: Herein, the polysaccharide species with antitumor effect were summarized in recent years, and the antitumor activity mechanisms of polysaccharides were analyzed and discussed.
Conclusion: Many polysaccharides have good antitumor activity, and they have broad application prospects.
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Cite this article as:
Chen Ling and Huang Gangliang *, Antitumor Activity of Polysaccharides: An Overview, Current Drug Targets 2018; 19 (1) . https://dx.doi.org/10.2174/1389450118666170704143018
DOI https://dx.doi.org/10.2174/1389450118666170704143018 |
Print ISSN 1389-4501 |
Publisher Name Bentham Science Publisher |
Online ISSN 1873-5592 |
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