Abstract
Background: Segmental medial arteriolysis (SAM) is a unique arteriopathy highlighted by significant lytic changes in the medial wall of the blood vessels and can present from vague gastrointestinal discomfort to catastrophic abdominal bleeding and shock. We hereby present a concise review of this rare phenomenon with historic perspectives, epidemiology, and current concepts of etiology, pathogenesis, relevant clinical associations, treatment modalities, prognosis and future directions in SAM.
Conclusion: In addition, we present an interesting occurrence of this intriguing phenomenon in a forty-eight year old lady at our institution who presented with vague symptomatology and was an extremely challenging diagnosis. This highlights the importance of timely detection and institution of therapeutic or preventive strategies to minimize future catastrophic events.
Keywords: Intriguing, mediolysis, segmental arterial, arteriopathy, stenoses, hyperlipidemia.
Cardiovascular & Hematological Disorders-Drug Targets
Title:The Intriguing Occurrence of Segmental Arterial Mediolysis: Case Report and Concise Literature Review
Volume: 17 Issue: 2
Author(s): Muhammad Ali Chaudhry *
Affiliation:
- Aultman Hospital, Canton, OH-44710,United States
Keywords: Intriguing, mediolysis, segmental arterial, arteriopathy, stenoses, hyperlipidemia.
Abstract: Background: Segmental medial arteriolysis (SAM) is a unique arteriopathy highlighted by significant lytic changes in the medial wall of the blood vessels and can present from vague gastrointestinal discomfort to catastrophic abdominal bleeding and shock. We hereby present a concise review of this rare phenomenon with historic perspectives, epidemiology, and current concepts of etiology, pathogenesis, relevant clinical associations, treatment modalities, prognosis and future directions in SAM.
Conclusion: In addition, we present an interesting occurrence of this intriguing phenomenon in a forty-eight year old lady at our institution who presented with vague symptomatology and was an extremely challenging diagnosis. This highlights the importance of timely detection and institution of therapeutic or preventive strategies to minimize future catastrophic events.
Export Options
About this article
Cite this article as:
Chaudhry Ali Muhammad *, The Intriguing Occurrence of Segmental Arterial Mediolysis: Case Report and Concise Literature Review, Cardiovascular & Hematological Disorders-Drug Targets 2017; 17 (2) . https://dx.doi.org/10.2174/1871529X17666170703115833
DOI https://dx.doi.org/10.2174/1871529X17666170703115833 |
Print ISSN 1871-529X |
Publisher Name Bentham Science Publisher |
Online ISSN 2212-4063 |
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
- Announcements
Related Articles
-
New Antihypertensive Drugs Under Development
Current Medicinal Chemistry Herbal and Traditional Chinese Medicine for the Treatment of Cardiovascular Complications in Diabetes Mellitus
Current Diabetes Reviews Addressing the Challenge: Current and Future Directions in Ovarian Cancer Therapy
Current Gene Therapy Matching Chelators to Radiometals for Positron Emission Tomography Imaging- Guided Targeted Drug Delivery
Current Drug Targets Sida cordifolia, a Traditional Herb in Modern Perspective – A Review
Current Traditional Medicine Cardiovascular Effects of Coumarins Besides their Antioxidant Activity
Current Topics in Medicinal Chemistry Processed Foods, Dysbiosis, Systemic Inflammation, and Poor Health
Current Nutrition & Food Science Modulation of Platelet Function and Signaling by Flavonoids
Mini-Reviews in Medicinal Chemistry A Novel Treatment Strategy for Sepsis and Septic Shock Based on the Interactions between Prostanoids, Nitric Oxide, and 20-Hydroxyeicosatetraenoic Acid
Anti-Inflammatory & Anti-Allergy Agents in Medicinal Chemistry Bradykinin Receptors in Ischemic Injury
Current Neurovascular Research Propofol and Systemic Inflammatory Response in Abdominal Aortic Surgery
Letters in Drug Design & Discovery Topical Antimicrobials for Burn Wound Infections
Recent Patents on Anti-Infective Drug Discovery Peripartum Cardiomyopathy: An Intensivist's Perspective
Current Women`s Health Reviews Clinical Management of the Cardiovascular Failure in Sepsis
Current Vascular Pharmacology Growing Collateral Arteries On Demand
Recent Patents on Cardiovascular Drug Discovery Endovascular Repair of Thoracic Aortic Aneurysms
Recent Patents on Cardiovascular Drug Discovery Reduction of Myocardial Ischemia-Reperfusion Injury with Pre- and Postconditioning: Molecular Mechanisms and Therapeutic Targets
Cardiovascular & Hematological Disorders-Drug Targets An Insight of Novel Pharmacological Therapies in Hypertrophic Cardiomyopathy
Medicinal Chemistry C-type Natriuretic Peptide (CNP): Cardiovascular Roles and Potential as a Therapeutic Target
Current Pharmaceutical Design Pharmacology of Adenosine A2A Receptors and Therapeutic Applications
Current Topics in Medicinal Chemistry