Background: Subcutaneous phaeohyphomycosis is an infection caused by
melanized fungi and is increasingly reported among immunosuppressive patients.
The most commonly cited etiologic agent is Exophiala jeanselmei, followed by Alternaria
spp. We present a case of subcutaneous phaeohyphomycosis in a 48-yearold
woman, with a history of lepromatous leprosy, using corticosteroid in immunosuppressive
doses due to a type 2 repetitive reaction leprosy outbreak.
Result and Discussion: The diagnosis was confirmed by fine-needle aspiration of
the secretion, with subsequent direct mycological observations, culture and molecular
analysis. The species agent was identified by culture and nucleotide sequences of
ribosomal DNA as Exophiala dermatitidis.