Title:Optimization of Drug Safety Profile in Inflammatory Bowel Disease Through a Personalized Approach
VOLUME: 19 ISSUE: 7
Author(s):Parambir S. Dulai and Corey A. Siegel*
Affiliation:University of California San Diego, San Diego, CA, Dartmouth-Hitchcock Medical Center, Lebanon, NH
Keywords:Crohn's disease, ulcerative colitis, risk, adverse events, inflammatory bowel disease, infections
Abstract:Treatment strategies and treatment options have changed considerably over the past decade
for Inflammatory Bowel Disease (IBD). Alongside this shift in therapeutic options has come an opportunity
to personalize treatment decisions based on individual patient profiles and preferences. One of
the most important aspects of therapy in IBD is treatment related risk, and an opportunity exists to
personalize therapy through optimization of drug safety profiles in individual patients. In this review
we discuss the potential risks of therapy in IBD, opportunities to mitigate those risks, and a personalized
approach to consider when using these agents in clinical practice.
