Background: Cardiovascular diseases (CVD) are the leading causes of death
Objective: The aim of this review is to evaluate several non-pharmacological approaches
to fight the development of CVD.
Results: Various strategies have been used to induce lifestyle changes in order to reduce
CVD development. In recent years, accumulating evidence has suggested that plant-foods
polyphenols, due to their biological properties, may be useful as supplement food for
treatments of the various aspects of CVD. Moreover, in addition to nutraceuticals supplementation,
several rehabilitation programs have been standardized to improve physical
function and reduce overall CVD risks. The scientific literature recommends the type of
exercise useful in patients with CVD. However, very little or nothing is known about the
individualized therapeutic dose for each risk profile.
Conclusion: To date, the efficacy of non-pharmacological strategies, as well as the optimal
rehabilitation program remains unclear. The present review highlights the effects of
personalizing the non-pharmacological intervention to contrast development and progression