Bioactive Flavonoids from Cornus mas L. Fruits

Author(s): Bianca Moldovan*, Luminita David

Journal Name: Mini-Reviews in Organic Chemistry

Volume 14 , Issue 6 , 2017


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Abstract:

Background: Cornus mas L. is a small tree of the Cornaceae plant family, widely spread in South Eastern Europe and Asia. The fruits of Cornus mas L. have been reported to possess anti-inflammatory, cardioand hepatoprotective, cytotoxic, antibacterial, antigenotoxic and diuretic effects. A high number of bioactive compounds have been identified in Cornus mas fruits, among which flavonoids exert favorable health effects especially by acting as potent antioxidants.

Method: The main step in the isolation of flavonoids from vegetal matrices is extraction. Apart the usually applied methods of organic compounds characterization like mass spectrometry (MS), ultraviolet and visible (UV-Vis) and infrared (IR) spectroscopy, the advanced analytical techniques such as high performance liquid chromatography (HPLC) and nuclear magnetic resonance (NMR) are reliable tools in flavonoids structure determination.

Conclusion: This review focuses on the recent published studies regarding the extraction, characterization and biological activities of flavonoids isolated from these fruits in order to understand their high potential as a source of bioactive compounds and their importance in developing new pharmacological products.

Keywords: Cornus mas, Cornelian cherries, flavonoids, extraction, chalcone synthase, biological activity.

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Article Details

VOLUME: 14
ISSUE: 6
Year: 2017
Published on: 16 November, 2017
Page: [489 - 495]
Pages: 7
DOI: 10.2174/1573398X13666170426102809
Price: $65

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