Introduction: The present study aimed at investigating the antimicrobial effect of
Ag/SiO2 embedded in (3-mercaptopropyl) trimethoxysilane (TPS) and tetraethyl orthosilicate
(TEOS) by employing the sol-gel method. The connection between the Ag/SiO2 and the
sol-gel matrix relied on the coordination bonds between the sulfur group at the top of the
TPS molecule and the silver atoms on the surface of Ag/SiO2 nanoparticles (NPs).
Method: In order to characterize the structure and the morphology of Ag/SiO2 nanocomposite
the field emission scanning of electron microscopy (FESEM), transmission electron microscopy
(TEM), X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FT-IR)
and atomic force microscopy (AFM) were used. The release of Ag+ ions under exposure to
water was investigated with the inductively coupled plasma (ICP) method after 21 days.
Result: The nanocomposite showed good antibacterial activity against some gram-positive
and gram-negative bacteria. The amount of silver release as Ag+ ions was found with the accuracy
of ICP analysis.
Conclusion: Furthermore, the low release new nanocomposite was found to have great potential
application in antibacterial activity.