Advances in Modern Medicine

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Advances in Modern Medicine introduces recent advanced medical practices performed at the Kure Medical Center and Chugoku Cancer Center (KMCCCC) - one of the leading hospitals in Japan - to those ...
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Efficacy of Wound Closure with Cyanoacrylate Glue for Total Knee Arthroplasty without Drain

Pp. 317-324 (8)

Yasunori Izuta, Masanori Yasumoto, Masahiro Yoshikawa, Manabu Niitani, Norikazu Hamada and Takashi Sugita


New surgical wound closure methods have been developed, and octyl-2- cyanoacrylate has been used for wound closure after surgery. In this study, we compared clinical outcomes for total knee arthroplasty with a new wound closure using cyanoacrylate glue without drain and conventional skin suture procedure with drain. Complications in the group of cyanoacrylate included one case of delayed skin healing. No case of blood transfusion, pulmonary embolism, deep-venous thrombosis, or deep infection existed. Concerning estimated blood loss, the group of cyanoacrylate decreased significantly at the time of post-op; 1 day and post-op, 3 days. This procedure had some benefits for patients and clinical staff.


Blood loss, Cyanoacrylate glue, Drainage, Total knee arthroplasty, Wound closure.


Dept. Orthopedic Surgery, National Hospital Organization, Kure Medical Center and Chugoku Cancer Center, 3-1 Aoyama-cho, Kure 737-0023, Japan.