Characteristics of Acute Cholangitis and Endoscopic Management of Elderly Patients at Our Institute
Pp. 296-305 (10)
Atsushi Yamaguchi, Toshiki Yamaguchi, Toshio Kuwai, Hirotaka Kouno and Hiroshi Kohno
The clinical presentation of acute cholangitis, etiology and complications
from endoscopic early biliary drainage in elderly patients was evaluated.
205 patients with acute cholangitis treated at the Kure Medical Center and Chugoku
Cancer Center were enrolled. Of these, 108 patients were 75 years old or older (elderly)
and 97 patients were younger than 75 years old. Patients’ clinical characteristics,
etiology and severity of cholangitis, and complications of endoscopic early biliary
drainage were compared between the elderly and younger cohorts.
There was a significant difference in severe cholangitis between elderly and younger
patients, at 17.6% and 0%, respectively. There was no significant difference in
complications between elderly and younger patients, and between patients with and
without early biliary drainage. One 91-year old woman with early biliary drainage had
post-ERCP (endoscopic retrograde cholangiopancreatography) aspiration pneumonia
Acute cholangitis in elderly patients may become severe in degree with a high
incidence. Early ERCP for elderly persons is relatively safe, but it should be done
carefully, not induce a consequent death due to complications such as aspiration
Acute cholangitis, Aspiration pneumonia, Biliary drainage, Complications,
Department of Gastroenterology, National Hospital Organization, Kure Medical Center and Chugoku Cancer Center, 3-1 Aoyama-cho, Kure 737-0023, Japan.