Advances in Modern Medicine

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Advances in Modern Medicine introduces recent advanced medical practices performed at the Kure Medical Center and Chugoku Cancer Center (KMCCCC) - one of the leading hospitals in Japan - to those ...
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A New Therapeutic Strategy for Advanced Squamous Cell Carcinomas of the Head and Neck

Pp. 3-11 (9)

DOI: 10.2174/9781681080239117010004

Author(s): Haruo Hirakawa, Yasuyuki Nishi, Taisuke Watanabe, Makoto Tada, Kiyomi Taniyama, Wataru Kamiike


A concurrent superselective intra-arterial chemoradiotherapy (SIACRT) is a new therapeutic strategy for advanced squamous cell carcinomas of the maxillary sinus and upper gingiva that might enable patients to keep the shape and function as well as improve curability. We have been applying SIACRT since 2008. We will present the results of SIACRT compared to conventional combined therapy at our hospital. SIACRT is promising to preserve patient’s quality of life (QOL) both under and after the treatment without sacrificing a cure rate.


Cisplatin, Head and neck cancer, Superselective intra-arterial chemoradiotherapy, 5-Fluorouracil.