Background: Tin-promoted allylation of carbonyl or imino groups is one of the most convenient
and efficient methods for synthesis of homoallylic compounds, which are versatile building blocks in the
preparation of many biologically active molecules and natural products.
Objective: This review provides an insight into one-pot allylation reactions for the synthesis of different homoallylic
compounds promoted by tin powder.
Conclusion: In the last four decades, tin powder-promoted allylation process has been exploited in synthesis of
homoallylic compounds. This multicomponent “one-pot” strategy avoids a lengthy separation process and purification
of the intermediate chemical compounds, which saves time and resources while increasing the chemical
yield. This tin-promoted process has the following features: operational simplicity, good tolerance to functional
groups and improved yields. The protocol could be carried out under wet conditions or even in pure water.