Green Synthetic Routes to Pharmaceutical Drugs

Author(s): Patricia G. Ferreira, Caroline D. Nicoletti, Fernando de C. da Silva, Vitor F. Ferreira*

Journal Name: Current Green Chemistry

Volume 3 , Issue 3 , 2016

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Graphical Abstract:


Background: Pharmaceutical companies produce synthetic drugs in complex multiple-step processes, but due to this high complexity, they generate a large amount of waste and consume high amounts of water and energy. The criticism of environmental agencies around the world has led to demands for changes in these processes.

Methods: With advances in new green reaction conditions and new manufacturing processes, these industries have lowered their impact on the environment. This paper addresses how pharmaceutical companies have developed alternative routes for some drugs within the precepts of green chemistry.

Keywords: Green drug design, sustainable synthesis, atom economy, biomass conversion, biomass-to-chemicals, pharmaceutical drugs.

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Article Details

Year: 2016
Published on: 27 April, 2017
Page: [259 - 276]
Pages: 18
DOI: 10.2174/2213346104666170130145445
Price: $25

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