Background: Advanced veterinary medical care's promote progress to improve the
health of our animals and enhance the efficiency of animal husbandry. Drugs present in tissue
can be ingested by humans, after being added to feed or premixed with it to prevent various
Objective: Diaveridine HCl (DVD), diaminopyimidine antimicrobial agent, has been
electroanalyzed at electrochemically activated ultrafine urethane (UT) electrode using square
wave voltammetry with well-known high sensitivity.
Method: The optimum conditions for electrochemical activation of UT electrode have been
explored. The effects of electrolyte pH and instrumental parameters on the electrochemical
behavior of DVD are optimized.
Results: At the optimum conditions, the rectilinear range for the DVD analysis was
constructed and found to extend over the range 1.68-16.4 µM. Both relative standard
deviation and confidence limit for six replicate measurements were calculated.
Conclusion: The electrochemical pre-treatment of UT via cycling of electrode in the
potential range -0.2-1.9 V was found to be the optimum; the maximum negative potential
shift with the larger peak current was obtained at the modified electrode at the optimum pH