An Overview of Currently Available Antimalarials

Author(s): Nikolay Yu. Gorobets*, Yuriy V. Sedash, Brajendra K. Singh, Poonam, Brijesh Rathi*

Journal Name: Current Topics in Medicinal Chemistry

Volume 17 , Issue 19 , 2017


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Graphical Abstract:


Abstract:

Background: Despite the substantial progress over the time, malaria remains a major public health concern and causing hundreds of thousands of deaths. Resistance to the available antimalarial therapy increases threat to the global public health.

Objective: Overview of currently available antimalarials.

Method: Literary survey.

Results: The summarized data about different types of antimalarial therapies and their efficiency and modes of action.

Conclusion: Despite the seemingly large number of the drugs currently available for malaria treatment, this arsenal is limited due to the narrow variation of their mechanism of action.

Keywords: Malaria, Antimalarial drugs, Drug resistance, Mechanism of action, Antimalarial therapy, Plasmodium.

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Article Details

VOLUME: 17
ISSUE: 19
Year: 2017
Page: [2143 - 2157]
Pages: 15
DOI: 10.2174/1568026617666170130123520
Price: $65

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