Abstract
Background: Despite the substantial progress over the time, malaria remains a major public health concern and causing hundreds of thousands of deaths. Resistance to the available antimalarial therapy increases threat to the global public health.
Objective: Overview of currently available antimalarials. Method: Literary survey. Results: The summarized data about different types of antimalarial therapies and their efficiency and modes of action. Conclusion: Despite the seemingly large number of the drugs currently available for malaria treatment, this arsenal is limited due to the narrow variation of their mechanism of action.Keywords: Malaria, Antimalarial drugs, Drug resistance, Mechanism of action, Antimalarial therapy, Plasmodium.
Current Topics in Medicinal Chemistry
Title:An Overview of Currently Available Antimalarials
Volume: 17 Issue: 19
Author(s): Nikolay Yu. Gorobets*, Yuriy V. Sedash, Brajendra K. Singh, Poonam and Brijesh Rathi*
Affiliation:
- Department of Chemistry of Heterocyclic Compounds, State Scientific Institution “Institute for Single Crystals”, National Academy of Science of Ukraine, Nauky ave. 60, Kharkiv, 61001,Ukraine
- Department of Chemistry, Hansraj College University Enclave, University of Delhi, Delhi-110007,India
Keywords: Malaria, Antimalarial drugs, Drug resistance, Mechanism of action, Antimalarial therapy, Plasmodium.
Abstract: Background: Despite the substantial progress over the time, malaria remains a major public health concern and causing hundreds of thousands of deaths. Resistance to the available antimalarial therapy increases threat to the global public health.
Objective: Overview of currently available antimalarials. Method: Literary survey. Results: The summarized data about different types of antimalarial therapies and their efficiency and modes of action. Conclusion: Despite the seemingly large number of the drugs currently available for malaria treatment, this arsenal is limited due to the narrow variation of their mechanism of action.Export Options
About this article
Cite this article as:
Gorobets Yu. Nikolay*, Sedash V. Yuriy, Singh K. Brajendra, Poonam and Rathi Brijesh*, An Overview of Currently Available Antimalarials, Current Topics in Medicinal Chemistry 2017; 17 (19) . https://dx.doi.org/10.2174/1568026617666170130123520
DOI https://dx.doi.org/10.2174/1568026617666170130123520 |
Print ISSN 1568-0266 |
Publisher Name Bentham Science Publisher |
Online ISSN 1873-4294 |
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