Title:Exploring 1,3,4-Oxadiazole Scaffold for Anti-inflammatory and Analgesic Activities: A Review of Literature From 2005-2016
VOLUME: 18 ISSUE: 3
Author(s):Gita Chawla*, Baby Naaz and Anees A. Siddiqui
Affiliation:Department of Pharmaceutical Chemistry, School of Pharmaceutical Education and Research, Jamia Hamdard (Hamdard University), Hamdard Nagar, New Delhi 110062, Department of Pharmaceutical Chemistry, School of Pharmaceutical Education and Research, Jamia Hamdard (Hamdard University), Hamdard Nagar, New Delhi 110062, Department of Pharmaceutical Chemistry, School of Pharmaceutical Education and Research, Jamia Hamdard (Hamdard University), Hamdard Nagar, New Delhi 110062
Keywords:Analgesic, anti-inflammatory, scaffold, COX, 1, 3, 4-Oxadiazole, NSAIDs.
Abstract:1,3,4-Oxadiazole derivatives are found to have a wide range of pharmacological activities
and attracting the researchers to work on this nucleus. Literature survey indicates that many 1,3,4-
oxadiazoles have been synthesized with the aim to get compounds of significant anti-inflammatory
and analgesic activities with reduced adverse effects. The purpose of this review is to compile the
reports on 1,3,4-oxadiazole derivatives possessing anti-inflammatory and analgesic activities. The
review also includes the reports on 1,3,4-oxadiazole derivatives of existing NSAIDs in the last ten
years.
