Aim and Objective: Gene selection method as an important data preprocessing work has
been followed. The criteria Maximum relevance and minimum redundancy (MRMR) has been
commonly used for gene selection, which has a satisfactory performance in evaluating the correlation
between two genes. However, for viewing genes in isolation, it ignores the influence of other genes.
Methods: In this study, we propose a new method based on sparse representation and MRMR
algorithm (SRCMRM), using the sparse representation coefficient to represent the relevance of genes
and correlation between genes and categories. The SRCMRMR algorithm contains two steps. Firstly,
the genes irrelevant to the classification target are removed by using sparse representation coefficient.
Secondly, sparse representation coefficient is used to calculate the correlation between genes and the
most representative gene with the highest evaluation.
Results: To validate the performance of the SRCMRM, our method is compared with various
algorithms. The proposed method achieves better classification accuracy for all datasets.
Conclusion: The effectiveness and stability of our method have been proven through various
experiments, which means that our method has practical significance.