Title:Methods of Screening-Purification and Antimicrobial Potentialities of Bacteriocin in Health Care
VOLUME: 18 ISSUE: 9
Author(s):Varish Ahmad, Qazi Mohammad Sajid Jamal, Mughees Uddin Siddiqui, Arun K. Shukla, Mohammad A. Alzohairy, Mohammad A. Al Karaawi and Mohammad Amjad Kamal*
Affiliation:Nanomedicine& Nanobiotechnology Lab, Department of Biosciences, Integral University, Kursi Road, Dasauli, Lucknow- 226026, Department of Health Information Management, College of Applied Medical Sciences, Buraydah Colleges, Al Qassim, Department of Health Information Management, College of Applied Medical Sciences, Buraydah Colleges, Al Qassim, King Abdullah Institute for Nanotechnology, King Saud University, P.O. Box 2455, Riyadh 11451, Department of Medical Laboratory, College of Applied Medical Sciences, Qassim University, Al Qassim, Department of Medical Laboratory, College of Applied Medical Sciences, Buraydah Colleges, Al Qassim, King Fahd Medical Research Center, King Abdulaziz University, P. O. Box 80216, Jeddah 21589
Keywords:Bacteriocin, screening, purification, antimicrobial, therapeutics potentialities, health care.
Abstract:Background: Bacteriocin have been tested as safe and effective alternative molecules over the currently
used chemotherapeutic agents. Thus, being an important clinical significance, its screening and recovery methods
along with its application are poorly described. Therefore, their screening, purification strategies and utilities must
me extended. Thus, in this review, we, summarize potential application, various screening and purification methods
used for recovery of bacteriocins.
Methods: To complete this review, many reviews and previously published reports were studied. We, concentrated
on review question and exclusion and inclusion criteria. The quality of content was evaluated by the quality the
quality contents evaluation method. The standard method is used to describe the useful contents of available resources
and appraised.
Results: One hundred twenty research and review reports were used to complete this report. Sixty reports were used
to make a collective information on screening and production of Bacteriocin Eighty two papers were used to explore
the antimicrobial, therapeutic, diagnostic etc potentialities of bacteriocin in diverse field. The summarize form of
data also presented in the form of tables and figures. This review describes the various methods and parameters that
must be considered during the screening and purification methods. Moreover, the useful information is collected in
regard represent it therapeutic potentialities in various fields for the welfare of human being.
Conclusions: The conclusion of this review presented the significance of a fundamental framework for planning to
understanding the basic requirement needed for fast, cost effective screening and purification of bacteriocins. The
summered area of their utilities also helpful to extend the research field of bacteriocin. Thus, this report would be
useful not only to scale up the screening and production strategies faster at economical rate, but also provides a
platform to extend the research field of bacteriocin in many ways.
