Sonication-Assisted Nanoprecipitation in Drug Delivery

Author(s): Anh Thi Ngoc Vo, Thinh Duc Luu, Minh Ngoc Uyen Nguyen, Toi Van Vo, Wei Duan, Phuong Ha-Lien Tran, Thao Truong-Dinh Tran

Journal Name: Current Drug Metabolism

Volume 18 , Issue 2 , 2017

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Abstract:

Sonication-assisted nanoprecipitation provides an effective tool for nanomedicine engineering in therapeutic improvement. In the scope of this review, original works in interdisciplinary areas of using sonication with precipitation method for nanoparticulate drug delivery systems and its applications in management of different diseases are discussed. The use of sonication-assisted nanoprecipitation has been proved to improve drug bioavailability, which attracts tremendous interests as an effective strategy for drug delivery. However, many challenges still remain. To overcome these barriers, different approaches such as precipitation method, rational design, optimization and modification have been investigated. Accordingly, current knowledge of sonication-assisted nanoprecipitation proposes a broad perspective and optimization for the applications of nanotechnology in drug delivery.

Keywords: Nanoprecipitation, sonication, ultrasonication, drug delivery.

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Article Details

VOLUME: 18
ISSUE: 2
Year: 2017
Page: [145 - 156]
Pages: 12
DOI: 10.2174/1389200218666170116103555
Price: $65

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