Objective: In the present study, the essential oil of Athroisma proteiformis was characterized
for the first time.
Method: GC-HRMS (Gas Chromatography-High Resolution Mass Spectrometry) was performed for
qualitative and quantitative analysis of the phytochemicals present in the extract. Chemical analyses
were conducted to evaluate the total phenols, total flavonoids and antioxidant activity of the extract.
Results: Of the 130 peaks detected, 50 were studied and 30 compounds were clearly identified. The
main components of the extract were p-cymen-8-ol, the major compound (13.37%), followed by
caryophyllene oxide (12.02%), o-cymene (7.79%), humulene epoxide II (7.62%) and limonene
(7.35%). The essential oil of Athroisma proteiformis
exhibited a good antioxidant activity. The
Athroisma extract IC50
values were lower than those of the antioxidant standards used in the FRAP
and ABTS tests, ascorbic acid and BHT, and lower than glutathione in the OH radical reducing
power test. On the contrary, in the DPPH test, IC50
was higher for A. proteiformis
than for ascorbic
acid or BHT.
Conclusion: It can be concluded that the A. proteiformis
plant can be used as a source of natural antioxidants
but the consequences on human health should first be carefully studied due to the large
number of compounds present in the oil.