A Brief Overview on Chemistry and Biology of Benzoxepine

Author(s): Naveen Kuntala, Jhonsee R. Telu, Jaya S. Anireddy, Sarbani Pal*

Journal Name: Letters in Drug Design & Discovery

Volume 14 , Issue 9 , 2017

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Abstract:

Background: The present review article is related to the synthesis and medicinal importance of benzoxepine and its derivatives. The study of heterocycles is an evergreen field in the branch of organic / medicinal chemistry and always attracts the attention of chemists working not only in the area of organic synthesis but also in natural products.

Methodology: The derivatives of benzoxepine exhibit a wide range of pharmacological properties such as antibacterial, anticancer, antioxidants, anti-inflammatory, anti-diabetic, antiviral, antiproliferative, antituberculosis, antispermetogenic and antipsychotic activities. Consequently, their syntheses have attracted significant interest. Various methodologies have been developed for the synthesis and functionalization of this class of compounds.

Conclusion: In the present article, the relevant and recent advances in the field will be briefly covered.

Keywords: Benzoxepine, heterocycles, synthesis, medicinal importance, chemistry, biology.

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Article Details

VOLUME: 14
ISSUE: 9
Year: 2017
Page: [1086 - 1098]
Pages: 13
DOI: 10.2174/1570180814666161227125227
Price: $65

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