Title:Recent Trends in Nanotechnology-Based Drugs and Formulations for Targeted Therapeutic Delivery
VOLUME: 10 ISSUE: 2
Author(s):Hafiz M. N. Iqbal*, Angel M.V. Rodriguez*, Rekha Khandia*, Ashok Munjal* and Kuldeep Dhama*
Affiliation:ENCIT - Science, Engineering and Technology School, Tecnologico de Monterrey, Ave. Eugenio Garza Sada 2501, Monterrey, N.L., CP 64849, ENCIT - Science, Engineering and Technology School, Tecnologico de Monterrey, Ave. Eugenio Garza Sada 2501, Monterrey, N.L., CP 64849, Department of Biochemistry and Genetics, Barkatullah University, Bhopal-462 026 (MP), Department of Biochemistry and Genetics, Barkatullah University, Bhopal-462 026 (MP), Division of Pathology, ICAR-Indian Veterinary Research Institute, Izatnagar, Bareilly 243122, Uttar Pradesh
Keywords:Biomaterials, biomedical sector, drug delivery, drug-loaded nanoparticles, nanotechnology, therapeutic approaches.
Abstract:Background: In the recent past, a wider spectrum of nanotechnologybased
drugs or drug-loaded devices and systems has been engineered and investigated
with high interests.
Objective: The key objective is to help for an enhanced/better quality of patient life in
a secure way by avoiding/limiting drug abuse, or severe adverse effects of some in
practice traditional therapies.
Method: Various methodological approaches including in vitro, in vivo, and ex vivo
techniques have been exploited, so far. Among them, nanoparticles-based therapeutic
agents are of supreme interests for an enhanced and efficient delivery in the current
biomedical sector of the modern world.
Results: The development of new types of novel, effective and highly reliable therapeutic drug delivery
system (DDS) for multipurpose applications is essential and a core demand to tackle many human health
related diseases. In this context, nanotechnology-based several advanced DDS have been engineered with
novel characteristics for biomedical, pharmaceutical and cosmeceutical applications that include but not
limited to the enhanced/improved bioactivity, bioavailability, drug efficacy, targeted delivery, and therapeutically
safer with an extra advantage of overcoming demerits of traditional drug formulations/designs.
This review work is focused on recent trends/advances in nanotechnology-based drugs and formulations
designed for targeted therapeutic delivery. Moreover, information is also reviewed and given from recent
patents and summarized or illustrated diagrammatically to depict a better understanding. Recent patents
covering various nanotechnology-based approaches for several applications have also been reviewed.
Conclusion: The drug-loaded nanoparticles are among versatile candidates with multifunctional characteristics
for potential applications in biomedical, and tissue engineering sector.
