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Clinical Immunology, Endocrine & Metabolic Drugs (Discontinued)

Editor-in-Chief

ISSN (Print): 2212-7070
ISSN (Online): 2212-7089

Review Article

Macrogols: A Misleading Cause of Drug Hypersensitivity Diagnosis

Author(s): Gianfranco Calogiuri*, Caterina Foti, Maria Beatrice Bilo and Lene Heise Garvey

Volume 4, Issue 1, 2017

Page: [9 - 13] Pages: 5

DOI: 10.2174/2212707004666161209161535

Price: $65

Abstract

Background: Polyethylene Glycols (PEGs) or macrogols are reputed to be inert and nonimmunogenic substances, however they are reported to induce immediate type hypersensitivity reactions. Due to their widespread use in extensively consumed products as cosmetics and drugs, the attention towards these substances is still low.

Conclusion: Therefore, it may be useful to focus clinician's attention on possible adverse reactions caused by these polymers.

Keywords: Anaphylaxis, excipients, hypersensitivity, immediate-type reaction, macrogols, polyethylene glycols.

Graphical Abstract

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