Nowadays, the rational design of particles is an important issue in the development of pharmaceutical
medicaments. Advances in manufacturing methods are required to design new pharmaceutical particles with
target properties in terms of particle size, particle size distribution, structure and functional activity. Membrane
emulsification is emerging as a promising tool for the production of emulsions and solidified particles with tailored
properties in many fields.
In this review, the current use of membrane emulsification in the production of pharmaceutical particles is highlighted.
Membrane emulsification devices designed for small-scale testing as well as membrane-based methods
suitable for large-scale production are discussed. A special emphasis is put on the important factors that contribute
to the encapsulation efficiency and drug loading. The most recent studies about the utilization of the membrane
emulsification for preparing particles as drug delivery systems for anticancer, proteins/peptide, lipophilic
and hydrophilic bioactive drugs are reviewed.
Keywords: Membrane emulsification, emulsions, particles, drug delivery, encapsulation efficiency, stimulus responsive, administration
route, pharmaceutical field.
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