Core-shell Semiconductor Nanocrystals: Effect of Composition, Size, Surface Coatings on their Optical Properties, Toxicity and Pharmacokinetics

Author(s): Wafa' T. Al-Jamal

Journal Name: Current Pharmaceutical Design

Volume 23 , Issue 3 , 2017


Become EABM
Become Reviewer
Call for Editor

Abstract:

Quantum dots are semiconducting nanocrystals that exhibit extraordinary optical properties. QD have shown higher photostability compared to standard organic dye type probes. Therefore, they have been heavily explored in the biomedical field. This review will discuss the different approaches to synthesis, solubilise and functionalise QD. Their main biomedical applications in imaging and photodynamic therapy will be highlighted. Finally, QD biodistribution profile and in vivo toxicity will be discussed.

Keywords: Quantum dots, fluorescence, imaging, therapy, theranostic.

Rights & PermissionsPrintExport Cite as

Article Details

VOLUME: 23
ISSUE: 3
Year: 2017
Published on: 26 October, 2016
Page: [340 - 349]
Pages: 10
DOI: 10.2174/1381612822666161026164920
Price: $65

Article Metrics

PDF: 25
HTML: 3
EPUB: 1
PRC: 1