Background: On the basis that various substituted salicylamides have shown interesting
biological properties, we designed and synthesized new salicylamide derivatives with dipeptide
Methods: The synthesis was based on the gradual building of target molecules and provided
optically pure compounds.
Conclusion: The obtained compounds were tested for their antiproliferative effect against three
leukaemia cell lines in vitro and displayed GI50 values in the mid-micromolar range.