Increased Radioisotope Accumulation Around Pulmonary Arteriovenous Fistula Illustrated by Tc-99m-macroaggregated Albumin Scintigraphy and SPECT/CT in a Patient with Osler-Weber-Rendu Syndrome

Author(s): Shigeaki Higashiyama*, Joji Kawabe, Atsushi Yoshida, Kohei Kotani, Susumu Shiomi

Journal Name: Current Medical Imaging
Formerly: Current Medical Imaging Reviews

Volume 14 , Issue 1 , 2018

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Graphical Abstract:


Tc-99m-MAA scintigraphy was performed in a patient with pulmonary hypertension to confirm the presence of a Right-to-LEFT (R-L) shunt due to the pulmonary Arteriovenous (AV) fistula. Both planar imaging and SPECT/CT showed multiple decreased or increased RI accumulation in both lung fields, and the R-L shunt ratio was high, indicating the presence of an R-L shunt. We considered that the decreased RI accumulated lesions were caused by pulmonary hypertension due to the pulmonary AV fistula. Osler-Weber-Rendu syndrome was proposed and genetic diagnosis was done. However, we speculated that the increased RI accumulated lesions were attributable to localized bleeding or a venous telangiectasia around the pulmonary AV fistula.

Keywords: Osler-Weber-Rendu syndrome, pulmonary arteriovenous fistula, single-photon emission computed tomography/ computed tomography (SPECT/CT), Tc-99m-macroaggregated albumin (Tc-99m-MAA) scintigraphy, vascular malformations.

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Article Details

Year: 2018
Page: [151 - 153]
Pages: 3
DOI: 10.2174/1573405612666161018111353
Price: $65

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