Frontiers in Neurosurgery

Volume: 3

Brain Ischemic Stroke - From Diagnosis to Treatment

Indexed in: Scopus, EBSCO.

Stroke is thought to be the second biggest killer worldwide, and is responsible for over 5 million deaths per year. Several strategies have been developed to enhance treatment of stroke patients. ...
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Neurosurgery in Brain Ischemic Stroke

Pp. 170-184 (15)

Paolo Missori and Cristina Mancarella


Ischemic strokes caused by the complete occlusion of an intracranial artery are associated with poor outcomes overall, and high mortality rates. To improve the survival and the outcome otherwise not afforded by the available medical and interventional therapies a neurosurgical approach must be considered. In selected patients a microsurgical embolectomy and a decompressive craniectomy are effective therapies with which to treat occlusions of the middle cerebral artery or other territories when thrombolysis or an interventional endovascular embolectomy does not restore the vascular flow. A bypass procedure that employs a superficial temporal artery-to-middle cerebral artery (STA-to-MCA) surgical anastomosis can be performed to improve the blood flow in a deficient artery chronic angiopathic disorder.


Bypass, Decompressive craniectomy, Encephalo-myo-synangiosis, Ischemia, Intracranial pressure, Microsurgical embolectomy, Middle cerebral artery, Neurosurgery, Stroke.


Department of Neurology and Psychiatry, Neurosurgery, Policlinico Umberto I, “Sapienza” University of Rome, Italy.