Background: Pomegranate (Punica granatum L.) is a polyphenol-rich fruit with diverse medicinal
properties. Several lines of experimental and clinical evidence have shown that pomegranate intake helps lowering
blood pressure (BP) through different mechanisms.
Aims: This study aimed to present a narrative review on the anti-hypertensive properties of different parts of
pomegranate such as pomegranate juice (PJ), pomegranate peels (PP), pomegranate seed oil (PSO), pomegranate
fruit extract (PFE) and the mechanisms and phytochemicals responsible for these effects.
Methods: A review on the efficacy of consuming different parts of pomegranate (juice, peels, fruit extract and
seed oil) in lowering BP has been performed. To find relevant studies, a search in PubMed, Science Direct and
Scopus up from inception to May 4, 2015 was performed. Human, animals and in vitro studies investigating the
anti-hypertensive effects of pomegranate were included in the search.
Results: Findings arising from animal and clinical studies have shown pomegranate juice can reduce BP in both
short-term and long-term course. These effects are accompanied by antioxidant and anti-atherosclerotic actions
that collectively improve cardiovascular health. The anti-hypertensive effects have been reported for both pomegranate
juice and seed oil. Both systolic and diastolic pressures are affected.
Conclusion: Pomegranate juice possesses antioxidant, anti-hypertensive and anti-atherosclerotic properties.