Herein, we report a 70-year-old male patient, with recurrent multiple hepatic abscesses, that
was admitted to the internal medicine department for treatment of Carbapenem Resistant Escherichia
Coli (CRE) bacteremia.
The patient was treated with Tigecycline; few days later, he developed "Disseminated Intravascular
Coagulation (DIC)" like coagulation study abnormality that seemed to be related to Tigecycline
treatment. Upon discontinuing it, the DIC-like condition was resolved.
Tigecycline should be considered as a possible etiological factor in patients with DIC-like, and this
therapy should be withdrawn immediately in suspected cases.