Recent Progress on Synthesis and Anticancer Activity of 4-Thiazolidinone

Author(s): Sevil Senkardes, SG Guniz Kucukguzel

Journal Name: Mini-Reviews in Organic Chemistry

Volume 13 , Issue 5 , 2016

Become EABM
Become Reviewer

Graphical Abstract:


Abstract:

4-Thiazolidinones are sulphur analogues of oxazolidines. They are heterocyclic ring systems which have been explored for their antimicrobial, anticancer, anti-HCV, antifungal, anticonvulsant, antituberculosis, and other activities. While some earlier reviews on the biological activities of this ring system have been reported, the present review describes more recent synthetic strategies and medicinal aspects of 4-thiazolidinones as anticancer agents reported during the past few years (2010-2016).

Keywords: 4-Thiazolidinone, anticancer activity, cytotoxic, diflunisal, etodolac, flurbiprofen, synthesis.

Rights & PermissionsPrintExport Cite as

Article Details

VOLUME: 13
ISSUE: 5
Year: 2016
Page: [377 - 388]
Pages: 12
DOI: 10.2174/1570193X13666160826154159
Price: $65

Article Metrics

PDF: 27
HTML: 2
EPUB: 1