miRNA-Dependent Activation of mRNA Translation

Author(s): Wen-Juan Ni, Xiao-Min Leng

Journal Name: MicroRNA

Volume 5 , Issue 2 , 2016

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Graphical Abstract:


MicroRNAs (miRNAs) are small and important RNA molecules. They can regulate gene expression at different levels. Although their biogenesis has been well documented, elucidation of miRNA-dependent activation of mRNA translation has just begun. Here, we highlighted different patterns of miRNA-dependent activation of mRNA translation: miRNA can activate mRNA translation through binding different target sites; in different sub-cellular locations; under different cellular circumstances. MiRNA-dependent activation of mRNA translation suggests unexpected functions of miRNA, that could provide new clues in functional studies of other ncRNAs.

Keywords: Cellular circumstance, gene expression, miRNA, sub-cellular location, target site, translational activation.

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Article Details

Year: 2016
Published on: 07 November, 2016
Page: [83 - 86]
Pages: 4
DOI: 10.2174/2211536605666160825151201
Price: $65

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