Abstract
The male abnormal gene family contains 3 members, named mab21l1, mab21l2 and mab21l3. Since their first discovery in C. elegans, homologues of mab21l1 and mab21l2 have been found in Drosophila, Zebrafish, Xenopus, chicken, mouse and human. A number of studies have revealed that mab21 gene family members, mab21l1 and mab21l2, play important roles in regulating eye development. Here, we review the functions of the mab genes in regulating ocular development.
Keywords: Mab21, eye development, Pax-6, Mab21L1, Mab21L2.
Current Molecular Medicine
Title:The Male Abnormal Gene Family 21 (Mab21) Members Regulate Eye Development
Volume: 16 Issue: 7
Author(s): Z.-X. Huang, J.-W. Xiang, L. Zhou, Q. Nie, L. Wang, Z.-G. Chen, X.-H. Hu, Y. Xiao, W.-J. Qing, Y.-F. Liu, Q. Sun, X.-C. Tang, F.-Y. Liu, Z.-W. Luo, W.-B. Liu and D. W.-C. Li
Affiliation:
Keywords: Mab21, eye development, Pax-6, Mab21L1, Mab21L2.
Abstract: The male abnormal gene family contains 3 members, named mab21l1, mab21l2 and mab21l3. Since their first discovery in C. elegans, homologues of mab21l1 and mab21l2 have been found in Drosophila, Zebrafish, Xenopus, chicken, mouse and human. A number of studies have revealed that mab21 gene family members, mab21l1 and mab21l2, play important roles in regulating eye development. Here, we review the functions of the mab genes in regulating ocular development.
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Cite this article as:
Huang Z.-X., Xiang J.-W., Zhou L., Nie Q., Wang L., Chen Z.-G., Hu X.-H., Xiao Y., Qing W.-J., Liu Y.-F., Sun Q., Tang X.-C., Liu F.-Y., Luo Z.-W., Liu W.-B. and Li W.-C. D., The Male Abnormal Gene Family 21 (Mab21) Members Regulate Eye Development, Current Molecular Medicine 2016; 16 (7) . https://dx.doi.org/10.2174/1566524016666160824150729
DOI https://dx.doi.org/10.2174/1566524016666160824150729 |
Print ISSN 1566-5240 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5666 |
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