A Review on Pharmacological Properties of Coumarins

Author(s): Devulapally Srikrishna, Chandraiah Godugu, Pramod Kumar Dubey*

Journal Name: Mini-Reviews in Medicinal Chemistry

Volume 18 , Issue 2 , 2018


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Abstract:

The coumarin (benzopyran-2-one, or chromen-2-one) ring system, present in many natural products, displays diverse pharmacological properties. It has attracted the attention of chemists and medicinal chemists for decades. Many molecules based on the coumarin ring system have been described utilizing innovative synthetic methods. These synthetic routes have led to interesting analogues of coumarins which possess pharmacological activities like anti-HIV, antimicrobial, antiinflammatory, anticancer, anti-TB, anticonvulsant and MAO inhibitory properties. Details of these studies, correlating structure with biological activity are described in this review.

Keywords: Anticancer, anticonvulsant, anti-inflammatory, antimicrobial, antioxidant, coumarin, MAO inhibitory, pharmacological properties.

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Article Details

VOLUME: 18
ISSUE: 2
Year: 2018
Published on: 31 July, 2016
Page: [113 - 141]
Pages: 29
DOI: 10.2174/1389557516666160801094919
Price: $65

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