PEG-SO3H as Eco-friendly Polymeric Catalyst for the Synthesis of 2,3-Dihydroquinazolinones in Water

Author(s): Guoli Huang, Bo Liu, Mingyu Teng, Yegao Chen

Journal Name: Letters in Organic Chemistry

Volume 13 , Issue 6 , 2016

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Abstract:

A facile, efficient, green, and environmentally benign method is described for the synthesis of 2,3-dihydroquinazolin-4(1H)-ones by direct cyclocondensation of 2-aminobenzamide with aldehydes or ketones in water using PEG-SO3H as an acidic catalyst under room temperature. This new method totally avoids the use of organic acids, toxic or expensive solvents and affording the corresponding product in good to excellent yields in this reaction.

Keywords: PEG-SO3H, 2, 3-dihydroquinazolinones, water, synthesis.

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Article Details

VOLUME: 13
ISSUE: 6
Year: 2016
Page: [453 - 458]
Pages: 6
DOI: 10.2174/1570178613666160728101809
Price: $65

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